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SHIELD

Exceptional Protection of Fluorescent Proteins (FP) and Endogenous Molecular Information


   


Get the first step of tissue processing right with our easy & reliable solution kit

Superior Tissue Preservation

Versatile: Safeguards endogenous fluorescence, protein antigenicity, nucleic acids, and overall tissue architecture. Synergizes with a range of existing tissue processing approaches including SWITCH (Cell, 2015) and MAP (NBT, 2016). 


Easy, Fast & Reliable

Easy & Reliable: Superior tissue preservation vs. CLARITY, without the variability of hydrogel embedding. Compatible with both non-fixed and PFA-fixed tissues.

Fast: Streamlined protocol preserves samples in a matter of days with minimal steps.


Protects Tissue for Multi-Round Processing

Repeated Staining & Imaging: Protects tissue during FP-imaging and antibody labeling across individual rounds.




Available in 250mL and 500mL Kits

Each kit comes with:

SHIELD Epoxy

SHIELD Buffer

SHIELD ON 

250mL kit is for 8 mouse brains or samples of equivalent size

500mL kit is for 16 mouse brains or samples of equivalent size



     




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